Ventricular Assist Devices in Heart Failure: How to Support the Heart but Prevent Atrophy?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10293035" target="_blank" >RIV/00216208:11110/14:10293035 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/14:10293035 RIV/00023001:_____/14:00058909

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/63/63_147.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/63/63_147.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Ventricular Assist Devices in Heart Failure: How to Support the Heart but Prevent Atrophy?

Original language description

Ventricular assist devices (VAD) have recently established themselves as an irreplaceable therapeutic modality of terminal heart failure. Because of the worldwide shortage of donors, ventricular assist devices play a key role in modern heart failure therapy. Some clinical data have revealed the possibility of cardiac recovery during VAD application. On the other hand, both clinical and experimental studies indicate the risk of the cardiac atrophy development, especially after prolonged mechanical unloading. Little is known about the specific mechanisms governing the unloading-induced cardiac atrophy and about the exact ultrastructural changes in cardiomyocytes, and even less is known about the ways in which possible therapeutical interventions may affect heart atrophy. One aim of this review was to present important aspects of the development of VAD-related cardiac atrophy in humans and we also review the most significant observations linking clinical data and those derived from studie

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

63

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

147-156

UT code for WoS article

000336459800002

EID of the result in the Scopus database

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