Psychiatric disturbances in five patients with MELAS syndrome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10293638" target="_blank" >RIV/00216208:11110/14:10293638 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/14:10293638
Result on the web
<a href="http://www.psychiatriapolska.pl/uploads/images/PP_5_2014/1035ENGverMagner_PsychiatrPol2014v48i5.pdf" target="_blank" >http://www.psychiatriapolska.pl/uploads/images/PP_5_2014/1035ENGverMagner_PsychiatrPol2014v48i5.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Psychiatric disturbances in five patients with MELAS syndrome
Original language description
Objectives: Mitochondrial disorders of energetic metabolism (MD) represent a heterogeneous group of diseases manifesting at any age with a broad spectrum of clinical symptoms, including psychiatric disorders. Methods: The aim of the study was to characterize psychiatric symptoms and diagnoses in five patients with MELAS syndrome between the ages of 17 and 53 years. Results: Four of MELAS patients them harbored the prevalent mitochondrial DNA (mtDNA) mutation 3243A>G, and one patient had the mtDNA mutation 12706T>C. Three patients had positive family histories for MELAS syndrome. In one patient, depression was diagnosed as the first symptom of MELAS syndrome. Depression also preceded a stroke-like episode in one patient. Four patients had disturbed cognitive functions, confusional states occurred in three patients. One patient manifested psychotic (schizophrenia-like) symptoms. Conclusion: Mitochondrial disorders deserve consideration as part of the differential diagnosis, especially if
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FG - Paediatrics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT14156" target="_blank" >NT14156: New diagnostic algorithms for mitochondrial disorders in children</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Psychiatria Polska
ISSN
0033-2674
e-ISSN
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Volume of the periodical
48
Issue of the periodical within the volume
5
Country of publishing house
PL - POLAND
Number of pages
11
Pages from-to
1035-1045
UT code for WoS article
000346596500013
EID of the result in the Scopus database
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