Changes in activity of metabolic and regulatory pathways during germination of S-coelicolor

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10293640" target="_blank" >RIV/00216208:11110/14:10293640 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/14:00439959 RIV/44555601:13440/14:43886277 RIV/61388971:_____/14:00506585

Result on the web

<a href="http://dx.doi.org/10.1186/1471-2164-15-1173" target="_blank" >http://dx.doi.org/10.1186/1471-2164-15-1173</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1471-2164-15-1173" target="_blank" >10.1186/1471-2164-15-1173</a>

Result language

angličtina

Original language name

Changes in activity of metabolic and regulatory pathways during germination of S-coelicolor

Original language description

Background: Bacterial spore germination is a developmental process during which all required metabolic pathways are restored to transfer cells from their dormant state into vegetative growth. Streptomyces are soil dwelling filamentous bacteria with complex life cycle, studied mostly for they ability to synthesize secondary metabolites including antibiotics. Results: Here, we present a systematic approach that analyzes gene expression data obtained from 13 time points taken over 5.5 h of Streptomyces germination. Genes whose expression was significantly enhanced/diminished during the time-course were identified, and classified to metabolic and regulatory pathways. The classification into metabolic pathways revealed timing of the activation of specific pathways during the course of germination. The analysis also identified remarkable changes in the expression of specific sigma factors over the course of germination. Based on our knowledge of the targets of these factors, we speculate on

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC Genomics

ISSN

1471-2164

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

december

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

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UT code for WoS article

000347731600001

EID of the result in the Scopus database

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