Long-term effect of specific treatment of primary aldosteronism on carotid intima-media thickness
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10282812" target="_blank" >RIV/00216208:11110/15:10282812 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/15:00059327 RIV/00064165:_____/15:10282812
Result on the web
<a href="http://dx.doi.org/10.1097/HJH.0000000000000464" target="_blank" >http://dx.doi.org/10.1097/HJH.0000000000000464</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/HJH.0000000000000464" target="_blank" >10.1097/HJH.0000000000000464</a>
Alternative languages
Result language
angličtina
Original language name
Long-term effect of specific treatment of primary aldosteronism on carotid intima-media thickness
Original language description
Background: Aldosterone has been shown to substantially contribute to the accumulation of different types of collagen fibres and growth factors in the arterial wall, thus increasing wall thickness. A previous study showed reduction of increased common carotid intima-media thickness (IMT) in patients with primary aldosteronism 1 year after adrenalectomy. Our study in patients with primary aldosteronism was aimed at comparing the long-term effect of adrenalectomy vs. spironolactone therapy on common carotid IMT regression. Method: Forty-two patients with confirmed primary aldosteronism (21 with aldosterone-producing adenoma treated by unilateral laparoscopic adrenalectomy, 21 treated with spironolactone) were investigated by carotid ultrasound at baseline and 1 and 6 years after the specific treatment. Results: There was a decrease in common carotid IMT from 0.956 +/- 0.140 to 0.900 +/- 0.127 mm (-5.9%; P < 0.05) at 1 year and to 0.866 +/- 0.130 mm (-9.4%; P < 0.01) at 6 years after adre
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/NT14155" target="_blank" >NT14155: Effect of the specific treatment of primary aldosteronism on subclinical organ damage regression</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Hypertension
ISSN
0263-6352
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
874-882
UT code for WoS article
000351956700029
EID of the result in the Scopus database
2-s2.0-84938998959