Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294495" target="_blank" >RIV/00216208:11110/15:10294495 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/15:10294495 RIV/00064203:_____/15:10294495 RIV/00023736:_____/15:00011302
Result on the web
<a href="http://dx.doi.org/10.1186/s12943-015-0363-8" target="_blank" >http://dx.doi.org/10.1186/s12943-015-0363-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12943-015-0363-8" target="_blank" >10.1186/s12943-015-0363-8</a>
Alternative languages
Result language
angličtina
Original language name
Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing
Original language description
In chronic myeloid leukemia, the identification of individual BCR-ABL1 fusions is required for the development of personalized medicine approach for minimal residual disease monitoring at the DNA level. Next generation sequencing (NGS) of amplicons larger than 1000 bp simplified and accelerated a process of characterization of patient-specific BCR-ABL1 genomic fusions. NGS of large regions upstream and downstream the individual breakpoints in BCR and ABL1 genes, respectively, also provided information about the sequence variants such are single nucleotide polymorphisms.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11555" target="_blank" >NT11555: DNA fingerprinting in chronic myeloid leukemia</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Cancer
ISSN
1476-4598
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
duben
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
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UT code for WoS article
000353441500001
EID of the result in the Scopus database
2-s2.0-84928256572