Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294843" target="_blank" >RIV/00216208:11110/15:10294843 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.14670/HH-30.293" target="_blank" >http://dx.doi.org/10.14670/HH-30.293</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14670/HH-30.293" target="_blank" >10.14670/HH-30.293</a>
Alternative languages
Result language
angličtina
Original language name
Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds
Original language description
Detailed comparative analysis of at first sight not related process cascades is a means toward this aim: to trace common effector mechanisms and hereby eventually inspire innovative routes for therapeutic management. Following this concept, promotion oftumor progression by stroma, especially cancer-associated fibroblasts and smooth muscle actin-positive myofibroblasts, and beneficial activity of respective cells in wound healing have helped to delineate the involvement of endogenous lectins of the family of galectins. In addition to initiating conversion of fibroblasts to myofibroblasts, galectin-1 instructs the cells to produce a structurally complex extracellular matrix. This bioscaffold is useful for keratinocyte culture, also apparently operativein ameliorating wound healing. These functional aspects encourage to study in detail how lectin-(glycan) counterreceptor display is orchestrated. Such insights are assumed to have potential to contribute to rationally manipulate stem/prec
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Histology and Histopathology
ISSN
0213-3911
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
3
Country of publishing house
ES - SPAIN
Number of pages
17
Pages from-to
293-309
UT code for WoS article
000351203800004
EID of the result in the Scopus database
2-s2.0-84924331935