The harmful chemistry behind krokodil (desomorphine) synthesis and mechanisms of toxicity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294938" target="_blank" >RIV/00216208:11110/15:10294938 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.forsciint.2015.02.001" target="_blank" >http://dx.doi.org/10.1016/j.forsciint.2015.02.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.forsciint.2015.02.001" target="_blank" >10.1016/j.forsciint.2015.02.001</a>
Alternative languages
Result language
angličtina
Original language name
The harmful chemistry behind krokodil (desomorphine) synthesis and mechanisms of toxicity
Original language description
"Krokodil'' is the street name for the homemade injectable mixture that has been used as a cheap substitute for heroin. Its use begun in Russia and Ukraine and nowadays is being spread over several other countries. Desomorphine is the semi-synthetic opioid claimed to be the main component of krokodil and considered to be responsible for its psychoactive characteristics. The starting materials for desomorphine synthesis are codeine tablets, alkali solutions, organic solvent, acidified water, iodine and red phosphorus, all of which are easily available in retail outlets, such as supermarkets, drugstores, etc. The resulting product is a light brown liquid that is called krokodil. People who inject krokodil present a great variety of serious signs and symptoms, including thrombophlebitis, ulcerations, gangrene, and necrosis, quickly evolving to limb amputation and death. These effects are thought to result from the toxic components produced as byproducts during the homemade drug synthesis.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Forensic Science International
ISSN
0379-0738
e-ISSN
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Volume of the periodical
249
Issue of the periodical within the volume
April
Country of publishing house
IE - IRELAND
Number of pages
7
Pages from-to
207-213
UT code for WoS article
000351947300035
EID of the result in the Scopus database
2-s2.0-84923282607