Effect of dopaminergic medication on speech dysfluency in Parkinson's disease: a longitudinal study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10296532" target="_blank" >RIV/00216208:11110/15:10296532 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21230/15:00230709 RIV/00064165:_____/15:10296532

Result on the web

<a href="http://dx.doi.org/10.1007/s00702-015-1363-y" target="_blank" >http://dx.doi.org/10.1007/s00702-015-1363-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-015-1363-y" target="_blank" >10.1007/s00702-015-1363-y</a>

Result language

angličtina

Original language name

Effect of dopaminergic medication on speech dysfluency in Parkinson's disease: a longitudinal study

Original language description

Although speech dysfluencies have been hypothesized to be associated with abnormal function of dopaminergic system, the effects of dopaminergic medication on speech fluency in Parkinson's disease (PD) have not been systematically studied. The aim of thepresent study was, therefore, to investigate the long-term effect of dopaminergic medication on speech fluency in PD. Fourteen de novo PD patients with no history of developmental stuttering and 14 age- and sex-matched healthy controls (HC) were recruited. PD subjects were examined three times; before the initiation of dopaminergic treatment and twice in following 6 years. The percentage of dysfluent words was calculated from reading passage and monolog. The amount of medication was expressed by cumulative doses of l-dopa equivalent. After 3-6 years of dopaminergic therapy, PD patients exhibited significantly more dysfluent events compared to healthy subjects as well as to their own speech performance before the introduction of dopamine

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

<a href="/en/project/GAP102%2F12%2F2230" target="_blank" >GAP102/12/2230: Acoustic voice and speech analysis in patients with central nervous system disorders</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

—

Volume of the periodical

122

Issue of the periodical within the volume

8

Country of publishing house

AT - AUSTRIA

Number of pages

8

Pages from-to

1135-1142

UT code for WoS article

000358387200007

EID of the result in the Scopus database

2-s2.0-84938826826