Speech disorders in Parkinson's disease: early diagnostics and effects of medication and brain stimulation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00068025" target="_blank" >RIV/00159816:_____/17:00068025 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26220/17:PU123029 RIV/00216224:14110/17:00095693

Result on the web

<a href="http://dx.doi.org/10.1007/s00702-017-1676-0" target="_blank" >http://dx.doi.org/10.1007/s00702-017-1676-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-017-1676-0" target="_blank" >10.1007/s00702-017-1676-0</a>

Result language

angličtina

Original language name

Speech disorders in Parkinson's disease: early diagnostics and effects of medication and brain stimulation

Original language description

Hypokinetic dysarthria (HD) occurs in 90% of Parkinson&apos;s disease (PD) patients. It manifests specifically in the areas of articulation, phonation, prosody, speech fluency, and faciokinesis. We aimed to systematically review papers on HD in PD with a special focus on (1) early PD diagnosis and monitoring of the disease progression using acoustic voice and speech analysis, and (2) functional imaging studies exploring neural correlates of HD in PD, and (3) clinical studies using acoustic analysis to evaluate effects of dopaminergic medication and brain stimulation. A systematic literature search of articles written in English before March 2016 was conducted in the Web of Science, PubMed, SpringerLink, and IEEE Xplore databases using and combining specific relevant keywords. Articles were categorized into three groups: (1) articles focused on neural correlates of HD in PD using functional imaging (n = 13); (2) articles dealing with the acoustic analysis of HD in PD (n = 52); and (3) articles concerning specifically dopaminergic and brain stimulation-related effects as assessed by acoustic analysis (n = 31); the groups were then reviewed. We identified 14 combinations of speech tasks and acoustic features that can be recommended for use in describing the main features of HD in PD. While only a few acoustic parameters correlate with limb motor symptoms and can be partially relieved by dopaminergic medication, HD in PD seems to be mainly related to non-dopaminergic deficits and associated particularly with non-motor symptoms. Future studies should combine non-invasive brain stimulation with voice behavior approaches to achieve the best treatment effects by enhancing auditory-motor integration.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

<a href="/en/project/NV16-30805A" target="_blank" >NV16-30805A: Effects of non-invasive brain stimulation on hypokinetic dysarthria, micrographia, and brain plasticity in patients with Parkinson's disease</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Volume of the periodical

124

Issue of the periodical within the volume

3

Country of publishing house

AT - AUSTRIA

Number of pages

32

Pages from-to

303-334

UT code for WoS article

000394433100004

EID of the result in the Scopus database

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