Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10297944" target="_blank" >RIV/00216208:11110/15:10297944 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s13075-015-0764-5" target="_blank" >http://dx.doi.org/10.1186/s13075-015-0764-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13075-015-0764-5" target="_blank" >10.1186/s13075-015-0764-5</a>

Result language

angličtina

Original language name

Serum calprotectin (S100A8/9): an independent predictor of ultrasound synovitis in patients with rheumatoid arthritis

Original language description

Introduction: Calprotectin, a heterodimeric complex of S100A8/9 (MRP8/14), has been proposed as an important serum biomarker that reflects disease activity and structural joint damage in rheumatoid arthritis (RA). The objective of this cross-sectional study was to test the hypothesis that calprotectin is associated with clinical and ultrasound-determined disease activity in patients with RA. Methods: A total of 37 patients with RA (including 24 females, a mean disease duration of 20 months) underwent aclinical examination and 7-joint ultrasound score (German US-7) of the clinically dominant hand and foot to assess synovitis by grey-scale (GS) and synovial vascularity by power Doppler (PD) ultrasound using semiquantitative 0-3 grading. The levels of serum calprotectin and C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were determined at the time of the ultrasound assessment. We analysed the relationship between serum calprotectin level, traditional inflammatory marke

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Arthritis Research and Therapy

ISSN

1478-6354

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

September

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000361275000001

EID of the result in the Scopus database

2-s2.0-84941644183