Predictive factors for the presence of tumor cells in bone marrow and peripheral blood in breast cancer patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10312515" target="_blank" >RIV/00216208:11110/15:10312515 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/15:33155546 RIV/00064165:_____/15:10312515
Result on the web
<a href="http://dx.doi.org/10.4149/neo_2015_031" target="_blank" >http://dx.doi.org/10.4149/neo_2015_031</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2015_031" target="_blank" >10.4149/neo_2015_031</a>
Alternative languages
Result language
angličtina
Original language name
Predictive factors for the presence of tumor cells in bone marrow and peripheral blood in breast cancer patients
Original language description
Simultaneous detection of disseminated tumor cells (DTCs) and circulating tumor cells (CTCs) was shown to be associated with an especially poor prognosis and increased incidence of disease-related deaths in non-metastatic breast cancer patients. We analyzed the occurance of DTCs and CTCs in patients with primary breast cancer and evaluated the correlation of their presence with other prognostic markers and investigated the changes in DTCs/CTCs number at different time points during treatment. Blood of 50 patients with primary breast cancer were used for immunomagnetic separation and detection of circulating tumor cells using the commercial available system the AdnaTest Breast Cancer (TM) (AdnaGen GmbH, Langenhagen, Germany). Bone marrow aspirates from50 patients were analyzed for DTCs by immunocytochemistry using the pan-cytokeratin antibody conjugated with FITC (Monoclonal Anti-Cytokeratin antibody F3418, Sigma Aldrich). Our results support the use of DTCs/CTCs analysis in early brea
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
—
Volume of the periodical
62
Issue of the periodical within the volume
2
Country of publishing house
SK - SLOVAKIA
Number of pages
10
Pages from-to
259-268
UT code for WoS article
000362862400011
EID of the result in the Scopus database
2-s2.0-84943609394