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Predictive factors for the presence of tumor cells in bone marrow and peripheral blood in breast cancer patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10312515" target="_blank" >RIV/00216208:11110/15:10312515 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/15:33155546 RIV/00064165:_____/15:10312515

  • Result on the web

    <a href="http://dx.doi.org/10.4149/neo_2015_031" target="_blank" >http://dx.doi.org/10.4149/neo_2015_031</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4149/neo_2015_031" target="_blank" >10.4149/neo_2015_031</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Predictive factors for the presence of tumor cells in bone marrow and peripheral blood in breast cancer patients

  • Original language description

    Simultaneous detection of disseminated tumor cells (DTCs) and circulating tumor cells (CTCs) was shown to be associated with an especially poor prognosis and increased incidence of disease-related deaths in non-metastatic breast cancer patients. We analyzed the occurance of DTCs and CTCs in patients with primary breast cancer and evaluated the correlation of their presence with other prognostic markers and investigated the changes in DTCs/CTCs number at different time points during treatment. Blood of 50 patients with primary breast cancer were used for immunomagnetic separation and detection of circulating tumor cells using the commercial available system the AdnaTest Breast Cancer (TM) (AdnaGen GmbH, Langenhagen, Germany). Bone marrow aspirates from50 patients were analyzed for DTCs by immunocytochemistry using the pan-cytokeratin antibody conjugated with FITC (Monoclonal Anti-Cytokeratin antibody F3418, Sigma Aldrich). Our results support the use of DTCs/CTCs analysis in early brea

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neoplasma

  • ISSN

    0028-2685

  • e-ISSN

  • Volume of the periodical

    62

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    10

  • Pages from-to

    259-268

  • UT code for WoS article

    000362862400011

  • EID of the result in the Scopus database

    2-s2.0-84943609394