Risk Factors in Ovarian Cancer: A Brief Overview

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10320331" target="_blank" >RIV/00216208:11110/15:10320331 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Risk Factors in Ovarian Cancer: A Brief Overview
Original language description
The exact causes of the sporadic cases of the most malignant gynecological cancer, ovarian carcinoma, are still difficult to ascertain. However, they account for the vast majority of ovarian cancer cases (~ 85%). The remaining cases may be attributed togenetic alterations in genome, chromosomes, genes and regulatory factors. Within this group, germline mutations in BRCA1/2 and DNA mismatch repair genes are the best known genetic risk factors. The aim of the epidemiological studies is to find out the risk or protective factors, associated with the ovarian cancer. In this review, we focus on a brief survey of these factors, with emphasis put particularly on the genetic alterations, reproductive factors and life style factors along with dietary factors.Unfortunately, there is no factor found to be fully protective. On the other hand, there is also no factor known to result in 100% risk of development of ovarian cancer. Further investigations of factors associated with ovarian cancer are
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Handbook on Ovarian Cancer: Risk Factors, Therapies and Prognosis
ISBN
978-1-63483-925-9
Number of pages of the result
15
Pages from-to
1-15
Number of pages of the book
247
Publisher name
Nova Science Publishers
Place of publication
New York
UT code for WoS chapter
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