Cardiotoxicity of yew

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10322064" target="_blank" >RIV/00216208:11110/15:10322064 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/15:10322064
Result on the web
<a href="http://dx.doi.org/10.1016/j.crvasa.2014.11.003" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2014.11.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.crvasa.2014.11.003" target="_blank" >10.1016/j.crvasa.2014.11.003</a>

Result language
angličtina
Original language name
Cardiotoxicity of yew
Original language description
The Common Yew (Taxus baccata) is an ornamental tree. The taxine alkaloids contained in yew berries, needles or bark are poisonous. The lethal dose for an adult is reported to be 50 g of yew needles. Patients who ingest a lethal dose frequently die due to cardiogenic shock, in spite of resuscitation efforts. Although no specific therapy exists, in some patients the asystole phase can be overcome by instituting extracorporeal membrane oxygen therapy (ECMO). Therapeutic procedures reported in the literature are only referred to in published case reports and it is not self-evident whether they have been effective or whether the patient had ingested a non-lethal dose of the toxins. In our case report, we describe lethal intoxication by common yew needles in a suicide attempt and summarize the treatment options referred to in literature.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
—

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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