Study of silica-based electrospun nanofibers as a scaffold for human bone marrow mesenchymal stem cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10323239" target="_blank" >RIV/00216208:11110/15:10323239 - isvavai.cz</a>
Result on the web
<a href="http://www.nanocon.eu/files/proceedings/23/papers/4483.pdf" target="_blank" >http://www.nanocon.eu/files/proceedings/23/papers/4483.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Study of silica-based electrospun nanofibers as a scaffold for human bone marrow mesenchymal stem cells
Original language description
Electrospun nanofibers with their nanoscale structure and ability to mimic native extracellular matrix (ECM) harbor a great potential for biotechnology, biomedicine, and tissue engineering. Inorganic nanofibers, such as silica-based nanofibers, have attracted attention for their physical and chemical stability, surface functionalities and hydrophilic nature. In this study, we tested biodegradable SiO2 nanofibers prepared by sol-gel method and needleless electrospinning as a scaffold for human bone marrow mesenchymal stem cells (hMSC), cells which are promising for regenerative medicine. The nanofibers were tested for cytotoxicity and capability to support cell adhesion. For cytotoxicity testing, the nanofibers were incubated for 24 or 72 hours in phosphate-buffered saline (PBS) or cell culture media supplemented with serum. The eluate was then applied to hMSC for either 24 hours or 4 days and cytotoxicity was evaluated using MTT assay. While eluates from PBS-treated nanofibers had no e
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2015 - 7th International Conference on Nanomaterials - Research and Application, Conference Proceedings
ISBN
978-80-87294-63-5
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
419-423
Publisher name
TANGER Ltd.
Place of publication
Ostrava
Event location
Brno
Event date
Oct 14, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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