Circulating tumor cells: what we know, what do we want to know about them and are they ready to be used in clinics?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10360724" target="_blank" >RIV/00216208:11110/17:10360724 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/17:10360724 RIV/00064165:_____/17:10360724
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489883/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489883/</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Circulating tumor cells: what we know, what do we want to know about them and are they ready to be used in clinics?
Original language description
Circulating tumor cells (CTC) present in peripheral blood are assigned precursors of advanced tumor disease. Simplicity of blood withdrawal procedure adds practically an unlimited possibility of the CTC-monitoring and the advantages of the repeated biopsies over time. CTC got prognostic, predictive and diagnostic status with the technologic advance. Although the clinical utility of CTC has reached the high evidence, the significance of CTC testing was presented in the treatment strategy mostly with palliative intention. We report on the experiences with the CTC-testing in the CLIA-like laboratory working with the size-based CTC separation and in vitro culture. The data is presented in the form of case reports in patients with breast (BC), colorectal (CRC), prostate (PC) and lung cancer (NSCLC) to support the clinical utility of CTC during the neoadjuvant, adjuvant and palliative treatment. The presented findings support the evidence for liquid biopsy clinical implementation and enhance the ability of malignant disease monitoring and the treatment efficacy prediction.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Translational Research
ISSN
1943-8141
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
17
Pages from-to
2807-2823
UT code for WoS article
000404548300012
EID of the result in the Scopus database
2-s2.0-85021264497