Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10360825" target="_blank" >RIV/00216208:11110/17:10360825 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/17:10360825
Result on the web
<a href="http://www.cspatologie.cz/docs/866-fulltext.pdf" target="_blank" >http://www.cspatologie.cz/docs/866-fulltext.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report
Original language description
We report the case of a 44-year-old female with sebaceous adenoma arising in mature cystic teratoma of the ovary. The patient had a tumor in the left ovary; 125 x 90 x 70 mm. Microscopically, the tumor consisted of structures typical of dermoid cysts. However, large areas of sebaceous proliferation were found. These areas were comprised of sebaceous nodules with features similar to a sebaceous adenoma of the skin. Immunohistochemically, the tumor showed "wild-type" expression of p53 and low proliferative activity (Ki-67 index < 5%). To verify the possibility of Muir-Torre syndrome we performed immunohistochemical examination of DNA mismatch repair proteins expression. However, all four proteins examined (MSH2, MSH6, MLH1, PMS2) were positive. Sebaceous adenoma arising in mature teratoma of the ovary is rare. To the best of our knowledge, only six cases have been reported in the literature to date.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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