Sebaceous carcinoma of the breast: report of four cases and review of the literature

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10296028" target="_blank" >RIV/00216208:11140/15:10296028 - isvavai.cz</a>
Result on the web
<a href="http://www.termedia.pl/Original-paper-Sebaceous-carcinoma-of-the-breast-report-of-four-cases-and-review-of-the-literature,55,25523,1,1.html" target="_blank" >http://www.termedia.pl/Original-paper-Sebaceous-carcinoma-of-the-breast-report-of-four-cases-and-review-of-the-literature,55,25523,1,1.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5114/pjp.2015.53010" target="_blank" >10.5114/pjp.2015.53010</a>

Result language
angličtina
Original language name
Sebaceous carcinoma of the breast: report of four cases and review of the literature
Original language description
Sebaceous carcinoma of the breast is an exceedingly rare neoplasm. Little is known about the behavior and prognosis of this type of breast cancer. We report clinical, histological and immunohistochemical features of four cases of breast carcinoma with prominent (at least 50%) sebaceous differentiation. The tumors occurred in four women, aged 25-66, and were composed of cords, lobules and solid sheets of tumor cells with sebaceous differentiation, comprising 50-90% of the tumor mass. The second componentconsisted of cells with non-vacuolated cytoplasm, present mostly around the periphery of the lobules, or which formed separate tumor sheets with no evidence of sebaceous differentiation and were indistinguishable from a classical ductal carcinoma. Immunohistochemically, three tumors expressed hormone receptors; all cases were HER2-negative and had retained expression of the DNA mismatch repair proteins. Three patients had axillary lymph node metastases, and two patients had distant meta
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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