Emotion stimulus processing in narcolepsy with cataplexy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10360837" target="_blank" >RIV/00216208:11110/17:10360837 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/17:10360837

Result on the web

<a href="http://dx.doi.org/10.1111/jsr.12444" target="_blank" >http://dx.doi.org/10.1111/jsr.12444</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jsr.12444" target="_blank" >10.1111/jsr.12444</a>

Result language

angličtina

Original language name

Emotion stimulus processing in narcolepsy with cataplexy

Original language description

Reported brain abnormalities in anatomy and function in patients with narcolepsy with cataplexy led to a project based on qualitative electroencephalography examination and analysis in an attempt to find a narcolepsy with cataplexy-specific brain-derived pattern, or a sequence of brain locations involved in processing humorous stimuli. Laughter is the trigger of cataplexy in these patients, and the difference between patients and healthy controls during the laughter should therefore be notable. Twenty-six adult patients (14 male, 12 female) suffering from narcolepsy with cataplexy and 10 healthy controls (five male, five female) were examined. The experiment was performed using a 256-channel electroencephalogram and then processed using specialized software built according to the scientific research team&apos;s specifications. The software utilizes electroencephalographic data recorded during elevated emotional states in participants to calculate the sequence of brain areas involved in emotion processing using non-linear and linear algorithms. Results show significant differences in activation (pre-laughter) patterns between the patients with narcolepsy and healthy controls, as well as significant similarities within the patients and the controls. Specifically, gyrus orbitalis, rectus and occipitalis inferior are active in healthy controls, while gyrus paracentralis, cingularis and cuneus are activated solely in the patients in response to humorous audio stimulus. There are qualitative electroencephalographic-based patterns clearly discriminating between patients with narcolepsy and healthy controls during laughter processing.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/NT13238" target="_blank" >NT13238: Narcolepsy – clinical picture, pathophysiology, ageing, comorbidities and physical activity regimen</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Sleep Research

ISSN

0962-1105

e-ISSN

—

Volume of the periodical

26

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

30-37

UT code for WoS article

000397019800005

EID of the result in the Scopus database

2-s2.0-84981523709