Crosstalk of cell polarity signaling pathways

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10362292" target="_blank" >RIV/00216208:11110/17:10362292 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s00709-017-1075-2" target="_blank" >http://dx.doi.org/10.1007/s00709-017-1075-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00709-017-1075-2" target="_blank" >10.1007/s00709-017-1075-2</a>

Result language

angličtina

Original language name

Crosstalk of cell polarity signaling pathways

Original language description

Cell polarity, the asymmetric organization of cellular components along one or multiple axes, is present in most cells. From budding yeast cell polarization induced by pheromone signaling, oocyte polarization at fertilization to polarized epithelia and neuronal cells in multicellular organisms, similar mechanisms are used to determine cell polarity. Crucial role in this process is played by signaling lipid molecules, small Rho family GTPases and Par proteins. All these signaling circuits finally govern the cytoskeleton, which is responsible for oriented cell migration, cell shape changes, and polarized membrane and organelle trafficking. Thus, typically in the process of cell polarization, most cellular constituents become polarized, including plasma membrane lipid composition, ion concentrations, membrane receptors, and proteins in general, mRNA, vesicle trafficking, or intracellular organelles. This review gives a brief overview how these systems talk to each other both during initial symmetry breaking and within the signaling feedback loop mechanisms used to preserve the polarized state.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30106 - Anatomy and morphology (plant science to be 1.6)

Project

<a href="/en/project/GBP302%2F12%2FG157" target="_blank" >GBP302/12/G157: Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Conditions</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Protoplasma

ISSN

0033-183X

e-ISSN

—

Volume of the periodical

254

Issue of the periodical within the volume

3

Country of publishing house

AT - AUSTRIA

Number of pages

18

Pages from-to

1241-1258

UT code for WoS article

000399037400011

EID of the result in the Scopus database

2-s2.0-85015177351