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Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10363976" target="_blank" >RIV/00216208:11110/17:10363976 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/17:10363976

  • Result on the web

    <a href="http://dx.doi.org/10.3324/haematol.2016.151571" target="_blank" >http://dx.doi.org/10.3324/haematol.2016.151571</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3324/haematol.2016.151571" target="_blank" >10.3324/haematol.2016.151571</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement

  • Original language description

    Mature B-cell malignancies represent the most common types of hematologic tumors. Despite this, little information is available on the composition and function of hematopoiesis in patients with these malignancies. Hematopoietic stem and progenitor cells (HSPCs) might be influenced by at least three key factors: 1. HSPCintrinsic mutations (that might predispose subjects to the development of these malignancies), 2. Direct or indirect impact of malignant lymphocytes present in the bone marrow (BM) or extramedullary tissue, and 3. Age-related changes. The aim of the study herein was to analyze HSPC content in patients with thus far untreated mature B-cell malignancies.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Haematologica

  • ISSN

    0390-6078

  • e-ISSN

  • Volume of the periodical

    102

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    IT - ITALY

  • Number of pages

    4

  • Pages from-to

    "E152"-"E155"

  • UT code for WoS article

    000402488900009

  • EID of the result in the Scopus database

    2-s2.0-85017015763