Microbiome: A Potential Component in the Origin of Mental Disorders
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10363992" target="_blank" >RIV/00216208:11110/17:10363992 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/17:10363992
Result on the web
<a href="http://dx.doi.org/10.12659/MSM.905425" target="_blank" >http://dx.doi.org/10.12659/MSM.905425</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.12659/MSM.905425" target="_blank" >10.12659/MSM.905425</a>
Alternative languages
Result language
angličtina
Original language name
Microbiome: A Potential Component in the Origin of Mental Disorders
Original language description
It is not surprising to find microbiome abnormalities present in psychiatric disorders such as depressive disorders, bipolar disorders, etc. Evolutionary pressure may provide an existential advantage to the host eukaryotic cells in that it survives in an extracellular environment containing non-self cells (e.g., bacteria). This phenomenon is both positive and negative, as with other intercellular processes. In this specific case, the phenomenal amount of information gained from combined bacterial genome could enhance communication between self and non-self cells. This can be coupled to both pathological processes and healthy ones. In this review, we chose to examine potential associated disorders that may be coupled to the microbiome, from the perspective of their bidirectional communication with eukaryotic cells in the gut. Cognition, being the newest neural networking functionality to evolve, consumes a good amount of organismic energy, 30% of which arises from the gut flora. Furthermore, the mammalian gut is highly innervated and has a highly developed immune component, reflecting brain complexity. The brain-gut axis uses similar molecular messengers as the brain, which affects bacterial processes as well. Thus, any modification of normal bacterial processes may manifest itself in altered behavior/cognition, originating from the gut. The origin of some disorders associated with this bidirectional communication may be harnessed to restore normal functioning.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30215 - Psychiatry
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medical Science Monitor [online]
ISSN
1643-3750
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
June
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
3039-3043
UT code for WoS article
000403845600001
EID of the result in the Scopus database
2-s2.0-85021192719