Hypersensitivity Pneumonitis: Perspectives in Diagnosis and Management
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10364576" target="_blank" >RIV/00216208:11110/17:10364576 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/17:N0000016
Result on the web
<a href="http://dx.doi.org/10.1164/rccm.201611-2201PP" target="_blank" >http://dx.doi.org/10.1164/rccm.201611-2201PP</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1164/rccm.201611-2201PP" target="_blank" >10.1164/rccm.201611-2201PP</a>
Alternative languages
Result language
angličtina
Original language name
Hypersensitivity Pneumonitis: Perspectives in Diagnosis and Management
Original language description
Awareness of hypersensitivity pneumonitis (HP) as a unique disease entity dates back to the 18th century. Since then, numerous inciting agents have been attributed to inducing HP, and the pathogenesis of the disease is now better understood. HP is a disease of many facets and phenotypes, making its recognition and differentiation from other interstitial lung diseases (ILDs) challenging, in particular idiopathic pulmonary fibrosis (IPF). The clinician is often unable to distinguish features of chronic HP (CHP) from those of IPF, and some patients meeting the 2011 criteria for the diagnosis of IPF may in fact have CHP with pulmonary fibrosis. The high rate of screen failures in patients participating in IPF clinical trials highlights this diagnostic challenge, as pulmonologists may be misdiagnosing patients with CHP as having IPF, overlooking environmental factors that can contribute to the disease. Despite recent data and reports suggesting new directions in the diagnosis, management, and treatment of HP, there remain substantial gaps in knowledge of epidemiology, pathogenesis, optimal diagnostic approach, and, ultimately, classification of this disease. Consensus among experts for diagnosis, treatment, and management are lacking, and the need for consensus guidelines is evident. In this Perspective, we propose diagnostic criteria and a novel classification of HP based on a combination of international clinical experience and available evidence. We believe that these criteria will be of use to the pulmonologist when confronted with patients suspected of having HP and promote further study to increase our understanding of how HP should be managed. The proposed criteria need to be validated in further studies, and therefore should not be interpreted as a guideline recommendation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30203 - Respiratory systems
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Respiratory and Critical Care Medicine
ISSN
1073-449X
e-ISSN
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Volume of the periodical
196
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
680-689
UT code for WoS article
000410857700011
EID of the result in the Scopus database
2-s2.0-85029685953