M-4 Muscarinic Receptors and Locomotor Activity Regulation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10369382" target="_blank" >RIV/00216208:11110/17:10369382 - isvavai.cz</a>

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/66/66_S443.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/66/66_S443.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

M-4 Muscarinic Receptors and Locomotor Activity Regulation

Original language description

M-4 muscarinic receptors (M-4 MR) represent a subfamily of G-protein coupled receptors serving a substantial role in spontaneous locomotor activity regulation, cognition and modulation of cholinergic system. With increasing body of literature discussing the role of M-4 MR some controversies arose. Thus, we try here to summarize the current evidence regarding the M-4 MR, with the special focus on their role in locomotor activity control. We review the molecular function of M-4 MR in specific brain areas implicated in locomotor regulation, and shortly in other CNS processes that could be connected to locomotor activity. We also focus on brain areas implicated in locomotor activity biorhythm changes like suprachiasmatic nucleus, subparaventricular zone posterior hypothalamic area, striatum and thalamus. Gender-related aspects and differences in locomotor activity in males and females are discussed further.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/GA17-03847S" target="_blank" >GA17-03847S: The role of M4 muscarinic receptors in biorhythm regulation</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

66

Issue of the periodical within the volume

Supplement 4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

13

Pages from-to

"S443"-"S455"

UT code for WoS article

000422901400002

EID of the result in the Scopus database

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