Intramedullary ependymoma: long-term outcome after surgery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10376420" target="_blank" >RIV/00216208:11110/18:10376420 - isvavai.cz</a>
Alternative codes found
RIV/61383082:_____/18:00000401
Result on the web
<a href="https://doi.org/10.1007/s00701-017-3430-7" target="_blank" >https://doi.org/10.1007/s00701-017-3430-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00701-017-3430-7" target="_blank" >10.1007/s00701-017-3430-7</a>
Alternative languages
Result language
angličtina
Original language name
Intramedullary ependymoma: long-term outcome after surgery
Original language description
Background: Overall (OS) and progression-free survival (PFS) of patients undergoing spinal ependymoma resection has been frequently reported. Contrarily, OS and PFS of purely intramedullary ependymomas have not been clearly determined yet. Methods: The data of 37 patients undergoing resection of an intramedullary ependymoma (IE) from January 2000 to December 2016 were analysed retrospectively. Results: The mean age was 46 years. The male:female ratio was 24:13. The median duration of symptoms was 12 months. Sixty-two per cent of ependymomas were in the cervical, 24% in the thoracic, and 14% in the conus region in our series. The median volume was 1.3 ml. A syrinx was found in 49% and a cyst in 32%. GTR was achieved in 89%, STR in three (8%), and PR in one patient (3%). Median follow-up was 114 months. PFS was 87%, 82%, and 82% at 5, 10, and 15 years, respectively. OS was 97%, 88%, and 63% at 5, 10, and 15 years, respectively. There was a significant difference in PFS depending on the extent of resection and in OS depending on the pre-operative clinical status. There was no significant difference in OS and PFS regarding the other examined influencing factors. Conclusion: GTR resection was the most important factor influencing PFS. According to our results OS of IEs is much worse than that of spinal ependymomas. Our analysis confirms that patients with good pre-operative (McCormick grade 1 and 2) clinical status have significantly better OS than patients with McCormick grade 3 and higher.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Neurochirurgica
ISSN
0001-6268
e-ISSN
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Volume of the periodical
160
Issue of the periodical within the volume
3
Country of publishing house
AT - AUSTRIA
Number of pages
9
Pages from-to
439-447
UT code for WoS article
000424650500003
EID of the result in the Scopus database
2-s2.0-85039073482