Psychiatric manifestations in Wilson's disease: possibilities and difficulties for treatment

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10376759" target="_blank" >RIV/00216208:11110/18:10376759 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/18:10376759

Result on the web

<a href="https://doi.org/10.1177/2045125318759461" target="_blank" >https://doi.org/10.1177/2045125318759461</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/2045125318759461" target="_blank" >10.1177/2045125318759461</a>

Result language

angličtina

Original language name

Psychiatric manifestations in Wilson's disease: possibilities and difficulties for treatment

Original language description

Wilson&apos;s disease (WD) is an inherited metabolic disorder related to disturbances of copper metabolism, and predominantly presents with liver and neuropsychiatric symptoms. In most cases it can be successfully treated with anti-copper agents, and both liver function and neuropsychiatric symptoms typically improve. Treatment guidelines for WD include recommendations for anti-copper treatment as well as for the treatment of liver failure symptoms. Recently, recommendations for treatment of the neurological symptoms of WD have also been proposed. Although most WD patients present with psychiatric symptoms at some stage of the disease, currently there are no guidelines for the treatment of the psychiatric manifestations. Treatment of the psychiatric symptoms of WD is often guided by general psychiatric experience, which typically glosses over the specificity of WD, and can result in severe neurological and/or hepatic complications. Here we review and discuss the possible treatments available for the mood disturbances, psychosis, behavioral and cognitive disorders that can occur in WD, as well as their efficacy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Therapeutic advances in psychopharmacology

ISSN

2045-1253

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

13

Pages from-to

199-211

UT code for WoS article

000435917800002

EID of the result in the Scopus database

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