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Relative position of the atrioventricular canal determines the electrical activation of developing reptile ventricles

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10377525" target="_blank" >RIV/00216208:11110/18:10377525 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/18:00493024

  • Result on the web

    <a href="https://doi.org/10.1242/jeb.178400" target="_blank" >https://doi.org/10.1242/jeb.178400</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1242/jeb.178400" target="_blank" >10.1242/jeb.178400</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Relative position of the atrioventricular canal determines the electrical activation of developing reptile ventricles

  • Original language description

    Squamate reptiles appear to lack the specialized His-Purkinje system that enables the cardiac ventricle to be activated from apex to base as in mammals and birds. Instead, activation may simply spread from where the atrioventricular canal connects to the base. Gja5, which encodes Cx40, which allows fast impulse propagation, was expressed throughout the ventricles of developing anole lizards. Activation was optically recorded in developing corn snake and central bearded dragon. Early embryonic ventricles were broad in shape, and activation propagated from the base to the right. Elongated ventricles of later stages were activated from base to apex. Before hatching of the snake, the ventricle developed a cranial extension on the left and activation propagated from the base to the caudal apex and the cranial extension. In squamate reptiles, the pattern of electrical activation of the cardiac ventricle is dependent on the position of the atrioventricular canal and the shape of the ventricle.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30106 - Anatomy and morphology (plant science to be 1.6)

Result continuities

  • Project

    <a href="/en/project/GA16-02972S" target="_blank" >GA16-02972S: Elucidating cardiac conduction system formation with phylogenetic approaches</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Experimental Biology

  • ISSN

    0022-0949

  • e-ISSN

  • Volume of the periodical

    221

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

    000438916100019

  • EID of the result in the Scopus database

    2-s2.0-85048312946