Myocardial development in crocodylians
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F22%3A00565665" target="_blank" >RIV/67985823:_____/22:00565665 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10447668
Result on the web
<a href="https://doi.org/10.1002/dvdy.527" target="_blank" >https://doi.org/10.1002/dvdy.527</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/dvdy.527" target="_blank" >10.1002/dvdy.527</a>
Alternative languages
Result language
angličtina
Original language name
Myocardial development in crocodylians
Original language description
Background:Recent reports confirmed the notion that there exists a rudimentary cardiac conduction system (CCS) in the crocodylian heart, and development of its ventricular part is linked to septation. We thus analyzed myocardial development with the emphasis on the CCS components and vascularization in two different crocodylian species.Results:Using optical mapping and HNK-1 immunostaining, pacemaker activity was localized to the right-sided sinus venosus. The atrioventricular conduction was restricted to dorsal part of the atrioventricular canal. Within the ventricle, the impulse was propagated from base-to-apex initially by the trabeculae, later by the ventricular septum, in which strands of HNK-1 positivity were temporarily observed. Completion of ventricular septation correlated with transition of ventricular epicardial activation pattern to mature apex-to-base direction from two periapical foci. Despite a gradual thickening of the ventricular wall, no morphological differentiation of the Purkinje network was observed. Thin-walled coronary vessels with endothelium positive for QH1 obtained a smooth muscle coat after septation. Intramyocardial vessels were abundant especially in the rapidly thickening left ventricular wall.Conclusions:Most of the CCS components present in the homeiotherm hearts can be identified in the developing crocodylian heart, with a notable exception of the Purkinje network distinct from the trabeculae carneae.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10605 - Developmental biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Developmental Dynamics
ISSN
1058-8388
e-ISSN
1097-0177
Volume of the periodical
251
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
2029-2047
UT code for WoS article
000853874800001
EID of the result in the Scopus database
2-s2.0-85138082446