19F Magnetic Resonance Imaging of Injectable Polymeric Implants with Multiresponsive Behavior
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10378670" target="_blank" >RIV/00216208:11110/18:10378670 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/18:00492562
Result on the web
<a href="https://doi.org/10.1021/acs.chemmater.8b02115" target="_blank" >https://doi.org/10.1021/acs.chemmater.8b02115</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.chemmater.8b02115" target="_blank" >10.1021/acs.chemmater.8b02115</a>
Alternative languages
Result language
angličtina
Original language name
19F Magnetic Resonance Imaging of Injectable Polymeric Implants with Multiresponsive Behavior
Original language description
Recently, magnetic resonance imaging (MRI) probes based on fluorinated compounds have emerged as highly promising contrast agents. Direct imaging of injectable thermoresponsive polymer implants by 19F MRI represents an attractive, as yet unreported tool for the straightforward and non-invasive monitoring of implant localization, size, morphology, and biodegradation. Herein, we describe for the first time the in vivo 19f MRI visualization of such implants. These were subcutaneously and intramuscularly administered as an aqueous solution to form a traceable solid implant upon the change of temperature and pH. After formation, the polymer implant was effectively visualized by 19F MRI. The kinetics of the implant degradation is suitable for application as injectable drug depots or in the local radiotherapy of solid tumors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
<a href="/en/project/GA16-03156S" target="_blank" >GA16-03156S: Self-assembled polymeric nanostructures as bimodal magnetic resonance ultrasound contrast agents for imaging</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry of Materials
ISSN
0897-4756
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
15
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
4892-4896
UT code for WoS article
000442186500005
EID of the result in the Scopus database
2-s2.0-85050621317