Olfaction and Colour Vision: What Can They Tell Us about Parkinson's Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10381978" target="_blank" >RIV/00216208:11110/18:10381978 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/18:10381978
Result on the web
<a href="https://pmr.lf1.cuni.cz/media/pdf/pmr_2018119020085.pdf" target="_blank" >https://pmr.lf1.cuni.cz/media/pdf/pmr_2018119020085.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14712/23362936.2018.8" target="_blank" >10.14712/23362936.2018.8</a>
Alternative languages
Result language
angličtina
Original language name
Olfaction and Colour Vision: What Can They Tell Us about Parkinson's Disease
Original language description
Parkinson's disease is a neurodegenerative disorder with the pathological accumulation of alpha synuclein in the brain and peripheral nerve tissue. Early stages of synucleinopathies, often present clinically with rapid eye movement (REM) sleep disorder (RBD). Clinical markers that indicate early progression from RBD to manifest synucleinopathies include abnormal dopamine transporter (DAT) imaging, motor and non-motor symptoms. Despite the high diagnostic strength of DAT imaging and motor abnormalities, they are not the earliest biomarkers. Non-motor signs of neurodegeneration such as colour vision and olfaction abnormalities are detectable by clinical examination as early as 20 years before disease onset. Detailed analysis of olfactory and colour vision dysfunction can provide valuable information regarding brain pathologies, further specifying clinical phenotypes, and giving clues to underlying pathophysiological mechanisms in Parkinson's disease and related disorders.
Czech name
—
Czech description
—
Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
—
OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/NV16-28914A" target="_blank" >NV16-28914A: REM sleep behavior disorder – clinical presentation, disease course and its implications</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Prague Medical Report
ISSN
1214-6994
e-ISSN
—
Volume of the periodical
119
Issue of the periodical within the volume
2-3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
12
Pages from-to
85-96
UT code for WoS article
—
EID of the result in the Scopus database
2-s2.0-85056256343