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Clinical aspects of Alzheimer's disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F19%3A10400784" target="_blank" >RIV/00216208:11110/19:10400784 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023884:_____/19:00008215 RIV/00064165:_____/19:10400784

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XYz8V~i81Q" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XYz8V~i81Q</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.clinbiochem.2019.04.015" target="_blank" >10.1016/j.clinbiochem.2019.04.015</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Clinical aspects of Alzheimer's disease

  • Original language description

    Alzheimer&apos;s disease is a progressive, irreversible, incurable, neurodegenerative illness and the most common of the dementing disorders. It starts usually after 60 years of age and may span 8 to 12 years. The continuous and slow decline caused by this disease, is characterized by cognitive deterioration, loss of functional independence, changes in behaviour, and expanding needs for care. In the last three decades, the proteins predominating neuritic plaques and neurofibrillary tangles have been detected and researched: amyloid-beta protein in the plaques and hyperphosphorylated tau in the tangles. Alzheimer&apos;s disease is now considered a long-term process with a slow progress and with a prolonged development of pathological changes that precedes symptoms by years. AD is becoming one of the most problematic and expensive illness for the civilization, also known as &quot;silent threat&quot;.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    <a href="/en/project/GA17-05292S" target="_blank" >GA17-05292S: Novel blood-based biomarkers for early diagnosis, prognosis and progress of Alzheimer's disease</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Biochemistry

  • ISSN

    0009-9120

  • e-ISSN

  • Volume of the periodical

    72

  • Issue of the periodical within the volume

    October

  • Country of publishing house

    CA - CANADA

  • Number of pages

    4

  • Pages from-to

    3-6

  • UT code for WoS article

    000486413800002

  • EID of the result in the Scopus database

    2-s2.0-85064946174