Role of Interleukin-6 in Lung Complications in Patients With COVID-19: Therapeutic Implications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10415443" target="_blank" >RIV/00216208:11110/20:10415443 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/20:10415443
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ktvbn3i3o2" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ktvbn3i3o2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21873/invivo.11947" target="_blank" >10.21873/invivo.11947</a>
Alternative languages
Result language
angličtina
Original language name
Role of Interleukin-6 in Lung Complications in Patients With COVID-19: Therapeutic Implications
Original language description
COVID-19 is viral respiratory infection with frequently fatal lung complications in the elderly or in people with serious comorbidities. Lung destruction appears to be associated with a cytokine storm related to an increased level of interleukin-6 (IL6). Therapeutic targeting of the interleukin-6 signaling pathway can attenuate such a cytokine storm and can be beneficial for patients with COVID- 19 in danger of pulmonary failure. This article demonstrates the importance of IL6 in progression of disease and the possibility of inhibition of IL6 signaling in COVID-19 therapy.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
In Vivo
ISSN
0258-851X
e-ISSN
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Volume of the periodical
34
Issue of the periodical within the volume
Suppl. 3
Country of publishing house
GR - GREECE
Number of pages
4
Pages from-to
1589-1592
UT code for WoS article
000548901400002
EID of the result in the Scopus database
2-s2.0-85086051820