Changes in circulating stem cells and endothelial progenitor cells over a 12-month period after implantation of a continuous-flow left ventricular assist device
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10417776" target="_blank" >RIV/00216208:11110/20:10417776 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/20:43920781 RIV/00216208:11130/20:10417776 RIV/00064203:_____/20:10417776 RIV/00023001:_____/20:00080322
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Mp-AN4zMRV" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Mp-AN4zMRV</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5114/aoms.2020.100306" target="_blank" >10.5114/aoms.2020.100306</a>
Alternative languages
Result language
angličtina
Original language name
Changes in circulating stem cells and endothelial progenitor cells over a 12-month period after implantation of a continuous-flow left ventricular assist device
Original language description
Introduction: Changes in circulating CD34+CD45low stem cells (SC) and CD34+CD45low-FKDR+ endothelial progenitor cells (EPC) may reflect pathological endothelial activation. Non-pulsatile/continuous-flow left ventricular assist devices (CF-LVAD) can enhance this process. The aim of this study was to analyse the impact of 12-month CF-LVAD treatment on SC and EPC. Methods: We analysed changes in SC and EPC from the pre-implantation period up until 12 months after implantation over 3-month intervals in 14 patients. Data from 12 patients with heart failure (HF) and from 13 healthy volunteers were used as controls. Results: Baseline EPC were significantly higher in CF-LVAD and HF patients than in healthy controls, substantially decreasing 3 months after CF-LVAD implantation and then returning to high baseline values at 12 months. Conclusions: Changes in circulating SC and EPC may reflect pathological endothelial activation after CF-LVAD implantation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/NV16-27630A" target="_blank" >NV16-27630A: Markers of vascular health in patients with implanted mechanical circulatory support</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of Medical Science
ISSN
1734-1922
e-ISSN
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Volume of the periodical
16
Issue of the periodical within the volume
6
Country of publishing house
PL - POLAND
Number of pages
4
Pages from-to
1440-1443
UT code for WoS article
000585918400020
EID of the result in the Scopus database
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