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Ultrasound-guided perineural vs. peritendinous corticosteroid injections in carpal tunnel syndrome: a randomized controlled trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10425792" target="_blank" >RIV/00216208:11110/21:10425792 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/21:10425792 RIV/00216208:11130/21:10425792

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=HxD5vFfpWI" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=HxD5vFfpWI</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.23736/S1973-9087.21.06682-X" target="_blank" >10.23736/S1973-9087.21.06682-X</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ultrasound-guided perineural vs. peritendinous corticosteroid injections in carpal tunnel syndrome: a randomized controlled trial

  • Original language description

    BACKGROUND: Corticosteroid injections are proven to be effective in the management of carpal tunnel syndrome (CTS); however, the optimal injection site still remains unclear. AIM: To compare the efficacy of perineural vs. peritendinous target sites for corticosteroid injection in CTS. DESIGN: A Randomized, Single-Blind, Controlled Trial. SETTING: Outpatients, tertiary care center. POPULATION: Forty-six patients were equally randomized into two intervention groups as Group A (18 F and 5 M, mean age;50.0 +- 15.9 years, mean symptom duration;5.9 +- 3.3 months) and Group B (19 F, 4 M patients, mean age;54.3 +- 15.0 years, mean symptom duration;5.9 +- 4.7 months). METHODS: Methylprednisolone acetate (40 mg) and 1 mL of 1% trimecaine hydrochloride was injected next to the median nerve (Group A) or among flexor tendons away from the nerve (Group B) under ultrasound (US) guidance. The visual analogue scale was used as the primary outcome measure, and the symptom severity scale and functional status scale of the Boston Carpal Tunnel Questionnaire were used as the secondary subjective outcome measures. Twopoint discrimination, grip strength, cross-sectional area, and distal motor latency were assessed as objective outcome measures. The data were collected at baseline and at 2, 6 and 12 weeks after the injection. RESULTS: Both groups showed improvement in subjective and objective measures at 2 weeks following the injection - also maintained up to 12 weeks during the follow-up (p&lt;0.05). However, no difference was observed between the two groups (p&lt;0.05). No serious adverse effects were observed in either group. CONCLUSIONS: Both intervention techniques seem to be effective and safe in the conservative treatment of CTS. CLINICAL REHABILITATION IMPACT: Based on this study results, it might be noteworthy that physicians can opt for perineural or peritendinous injections without compromising the treatment efficacy and safety. Herewith, US guidance is, for sure, necessary for performing safe and accurate injections.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30306 - Sport and fitness sciences

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Physical and Rehabilitation Medicine

  • ISSN

    1973-9087

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    IT - ITALY

  • Number of pages

    8

  • Pages from-to

    775-782

  • UT code for WoS article

    000718320700013

  • EID of the result in the Scopus database

    2-s2.0-85115789922