Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F00%3A00003729" target="_blank" >RIV/00216208:11120/00:00003729 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1078/0065-1281-00573" target="_blank" >http://dx.doi.org/10.1078/0065-1281-00573</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1078/0065-1281-00573" target="_blank" >10.1078/0065-1281-00573</a>
Alternative languages
Result language
angličtina
Original language name
Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes
Original language description
n lymph nodes, dendritic cells form a complex meshwork and are linked by intercellular junctions. Intercellular junctions contribute to the integrity of lymphatic follicles and can potentially be affected by malignant processes in neighbouring B cells. We examined whether transmembrane molecules that constitute "adherens junctions" are present in follicular dendritic cells of normal human lymph nodes. We found that follicular dendritic cells but not interdigitating dendritic cells or sinus lining cellsexpressed cadherin molecules. Follicular dendritic cells also expressed beta -catenin but not vinculin. The cadherin molecules, which were identified in situ with the use of a monoclonal pan-cadherin antibody, were not recognized by antibodies to E-cadherin, N-cadherin or beta -cadherin. Intrafollicularly, cadherins were clearly colocalized with beta -catenins, in a dot-like fashion. We also detected intrafollicular expression of desmogleins and desmosomal plaque proteins. These findings
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/VS96129" target="_blank" >VS96129: Laboratory of gene expression</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2000
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Histochemica
ISSN
0065-1281
e-ISSN
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Volume of the periodical
102
Issue of the periodical within the volume
4
Country of publishing house
DE - GERMANY
Number of pages
16
Pages from-to
369-380
UT code for WoS article
000165865000001
EID of the result in the Scopus database
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