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A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F01%3A00003135" target="_blank" >RIV/00216208:11120/01:00003135 - isvavai.cz</a>

  • Result on the web

    <a href="http://ajpregu.physiology.org/content/280/1/R166.long" target="_blank" >http://ajpregu.physiology.org/content/280/1/R166.long</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A single bout of exercise induces beta-adrenergic desensitization in human adipose tissue

  • Original language description

    This study was designed to assess whether physiological activation of the sympathetic nervous system induced by exercise changes adipose tissue responsiveness to catecholamines in humans. Lipid mobilization in abdominal subcutaneous adipose tissue was studied with the use of a microdialysis method in 11 nontrained men (age: 22.3 +/- 1.5 yr; body mass index: 23.0 +/- 1.6). Adipose tissue adrenergic sensitivity was explored with norepinephrine, dobutamine (beta (1)-agonist), or terbutaline (beta (2)-agonist) perfused during 30 min through probes before and after 60-min exercise (50% of the maximal aerobic power). The increase in extracellular glycerol concentration during infusion was significantly lower after the exercise when compared with the increaseobserved before the exercise (P < 0.05, P < 0.02, and P < 0.01, respectively, for norepinephrine, dobutamine, and terbutaline).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IZ3611" target="_blank" >IZ3611: Effect of aerobic training programme on adrenergic regulation of lipolysis in fat tissue in obese subjects.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    American Journal of Physiology - Regulatory Integrative and Comparative Physiology

  • ISSN

    0363-6119

  • e-ISSN

  • Volume of the periodical

    280

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    "R166"-"R173"

  • UT code for WoS article

    000165955400022

  • EID of the result in the Scopus database