Language lateralization in monozygotic twins discordant for schizophrenia. Evidence from functional MRI

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F03%3A00007473" target="_blank" >RIV/00216208:11120/03:00007473 - isvavai.cz</a>

Alternative codes found

RIV/00023752:_____/03:00000321

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Language lateralization in monozygotic twins discordant for schizophrenia. Evidence from functional MRI

Original language description

Anatomical and functional studies have shown reduced cerebral asymmetry and functional lateralization in schizophrenia. The aim of this study was to assess the relative contribution of nongenetic factors in previously reported decreased language lateralization in schizophrenia using a co-twin control study. The authors examined the hemispheric dominance for language processing by means of functional MRI in four monozygotic twin pairs discordant for schizophrenia. Subjects were scanned while engaged in verbal fluency task. All twins were right-handed. The results indicate that language processing is less lateralized in affected twins compared with their well co-twins (a mean laterality index of 0,73 versus 0,90 respectively, difference p < 0,05). Differences in language lateralization between affected and well co-twins could suggest nongenetic neurodevelopmental reorganization within the network mediating language in twins with schizophrenia.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FL - Psychiatry, sexology

OECD FORD branch

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Project

<a href="/en/project/NF6794" target="_blank" >NF6794: Hippocampal impairment in schizophrenia: proton magnetic resonance spectroscopy study and dermatoglyphic analysis</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Psychiatrie

ISSN

1211-7579

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

3

Pages from-to

301-303

UT code for WoS article

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EID of the result in the Scopus database

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