Prevalence of HFE gene C282Y and H63D mutations and elevated iron biochemistries in patients with non-alcoholic fatty liver and alcoholic liver disease.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00001156" target="_blank" >RIV/00216208:11120/04:00001156 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Prevalence of HFE gene C282Y and H63D mutations and elevated iron biochemistries in patients with non-alcoholic fatty liver and alcoholic liver disease.
Original language description
We studied mutations of the HFE gene C282Y and H63D in patients with alcoholic liver cirrhosis and steatosis and in patients with non-alcoholic steatohepatitis and steatosis. We measured simultaneously the content of iron in liver tissue and biochemicalmarkers of iron metabolism in these groups of patients. The prevalence of both mutations in the two groups of patients did not differ significantly. There was no correlation between the studied gene mutations and the severity of liver injury.
Czech name
Výskyt mutací HFE genu C282Y a H63D a metabolizmus železa u nemocných s nealkoholickou steatohepatitidou a alkoholickou hepatopati
Czech description
Studovali jsme význam mutací HFE genu C282Y a H63D u nemocných s etylickou jaterní cirhózou a steatózou a u nemocných s non-alkoholickou steatohepatitidou a steatózou. Současně jsme stanovovali obsah železa v jaterní tkáni a biochemické markery metabolizmu železa u těchto skupin nemocných. Prevalence obou mutací v obou skupinách nemocných se významě nelišily a rovněž neměly signifikantní vztah ke stupni jaterního postižení.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Česká a slovenská gastroenterologie a hepatologie
ISSN
1213-323X
e-ISSN
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Volume of the periodical
58
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
89-93
UT code for WoS article
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EID of the result in the Scopus database
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