Long-term outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis with renal involvement

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F05%3A00001028" target="_blank" >RIV/00216208:11120/05:00001028 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Long-term outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis with renal involvement

Original language description

Despite treatment, renal involvement in antineutrophil cytoplasmic autoantibody (ANCA)-positive vasculitis is still associated with significant long-term mortality and remains an important cause of end-stage renal failure. Methods: We retrospectively analyzed a series of 61 consecutive patients with newly diagnosed ANCA-associated renal vasculitis (54.1% Wegener's granulomatosis, 23% renal-limited vasculitis, 16.4% microscopic polyangiitis, 4.9% Churg-Strauss syndrome) diagnosed between 1986 and 1997. Results: The median creatinine level at diagnosis was 221.5 (63-762) ? mol/l, i.e. 2.5 (0.7-8.6) mg/dl, 32.8% were dialysis-dependent. All patients were treated with cyclophosphamide. Remission was achieved in 87% of patients. Relapses occurred in 44.7%.The median renal disease-free interval was 62.5 (0-138) months. The estimated patient survival at 5 and 10 years was 78.3 and 62.2%, respectively. Mortality was associated with age (p = 0.04 when age limit 50 years) and advanced renal fai

Czech name

Dlouhodobé výsledky pacientů s antineutrofilní cytoplazmickou autoantibody asociovanou vaskulitidou s renálním postižením

Czech description

Autoři předkládají výsledky dlouhodobého slednování pacientů s antineutrofilní cytoplazmickou autoantibody asociovanou vaskulitidou s renálním postižením

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

—

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Kidney & Blood Press Research

ISSN

1420-4096

e-ISSN

—

Volume of the periodical

28

Issue of the periodical within the volume

3

Country of publishing house

CH - SWITZERLAND

Number of pages

9

Pages from-to

—

UT code for WoS article

000229576000003

EID of the result in the Scopus database

—