Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F08%3A00002131" target="_blank" >RIV/00216208:11120/08:00002131 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Detection of MMP-2 and MMP-9 in Normal Uncomplicated Pregnancy
Original language description
The invasion of extravillous trophoblast cells into the maternal endometrium is one of the key events in human placentation. The ability of these cells to infiltrate the uterine wall and to anchor the placenta to it as well as their ability to infiltrateand adjust utero-placental vessels to pregnancy depends, among other things, on their ability to secrete enzymes that degrade the extracellular matrix. Most of these enzymes belong to the family of matrix metal loproteinases. Matrix metal loproteinases(MMPs) belong to secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. This assay can be used in detecting MMP activity in biological samples using a EDANS/DABCYL fluorescence resonance energy transfer(FRET) peptide.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings of the 20th International Congress in Thrombosis
ISBN
978-88-7587-423-0
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
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Publisher name
Medimond
Place of publication
Bologna
Event location
Athens
Event date
Jan 1, 2008
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000263469000010