Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F10%3A00002449" target="_blank" >RIV/00216208:11120/10:00002449 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/10:00002449

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study

Original language description

Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study. Experimental Dermatology 2010. Abstract Introduction: Monitoring of circulating melanoma cells in the peripheral blood is a promising method for identifying a subgroup of patients with minimal residual disease. Objectives: To evaluate the prognostic impact of melanoma-associated antigens by multimarker real-time RT-PCR for disease-specific survival time. Methods: Fivemelanoma markers: Melan-A, gp100, MAGE-3, MIA and tyrosinase were detected by a quantitative multimarker real-time reverse transcription-PCR (RT-PCR). We included 65 patients with resected melanoma in stage II-III. Peripheral blood samples were examinedevery 3 months for 2 years. The expression of melanoma markers in 2925 RT-PCR assays was correlated with clinical staging results in total of 5 years. Results: Twenty-seven patients relapsed during the study period and 26 of them reveale

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FO - Dermatology and venereology

OECD FORD branch

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Project

<a href="/en/project/1A8243" target="_blank" >1A8243: Quantitative detection of circulating melanoma cells by real-time RT-PCR in patients treated for malignant melanoma</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental Dermatology

ISSN

0906-6705

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

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UT code for WoS article

000283373800007

EID of the result in the Scopus database

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