Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003156" target="_blank" >RIV/00216208:11120/11:00003156 - isvavai.cz</a>
Alternative codes found
RIV/75010330:_____/11:00009229
Result on the web
<a href="http://dx.doi.org/10.1007/s10637-009-9368-8" target="_blank" >http://dx.doi.org/10.1007/s10637-009-9368-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10637-009-9368-8" target="_blank" >10.1007/s10637-009-9368-8</a>

Result language
angličtina
Original language name
Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells
Original language description
The aim of the study is to compare the effects of new fluorinated taxanes SB-T-12851, SB-T-12852, SB-T-12853, and SB-T-12854 with those of the classical taxane paclitaxel and novel non-fluorinated taxane SB-T-1216 on cancer cells. Paclitaxel -sensitive MDA-MB-435 and paclitaxel-resistant NCI/ADR-RES human cancer cell lines were used. The new fluorinated taxanes appear to use the same or similar mechanisms of cell death induction as compared with SB-T-1216 and paclitaxel. New fluorinated and non-fluorinated taxanes are more effective against drug-resistant cancer cells than paclitaxel.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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