Cimetidine: An anticancer drug?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003161" target="_blank" >RIV/00216208:11120/11:00003161 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/11:#0000137
Result on the web
<a href="http://dx.doi.org/10.1016/j.ejps.2011.02.004" target="_blank" >http://dx.doi.org/10.1016/j.ejps.2011.02.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejps.2011.02.004" target="_blank" >10.1016/j.ejps.2011.02.004</a>

Result language
angličtina
Original language name
Cimetidine: An anticancer drug?
Original language description
Cimetidine, H2 receptor antagonists, is commonly prescribed for gastric and duodenal ulcer disease. Additionally, cimetidine has been shown to have anticancer effects. This review describes the mechanism of antitumor action of cimetidine including its ability to interfere with tumor cell adhesion, angiogenesis and proliferation; its effect on the immune system; as well as inhibition of postoperative immunosuppression. Its anticancer effect is also compared to that of the other H2 receptor antagonists aswell as outcomes of cimetidine in clinical studies in cancer patients.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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