Cortical Activation Changes during Repeated Laser Stimulation: A Magnetoencephalographic Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003316" target="_blank" >RIV/00216208:11120/11:00003316 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0019744" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0019744</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0019744" target="_blank" >10.1371/journal.pone.0019744</a>
Alternative languages
Result language
angličtina
Original language name
Cortical Activation Changes during Repeated Laser Stimulation: A Magnetoencephalographic Study
Original language description
Repeated warm laser stimuli produce a progressive increase of the sensation of warmth and heat and eventually that of a burning pain. The pain resulting from repetitive warm stimuli is mediated by summated C fibre responses. To shed more light on the cortical changes associated with pain during repeated subnoxious warm stimution, we analysed magnetoencephalographic (MEG) evoked fields in eleven subjects during application of repetitive warm laser stimuli to the dorsum of the right hand. One set of stimuli encompassed 10 laser pulses occurring at 2.5 s intervals. Parameters of laser stimulation were optimised to elicit a pleasant warm sensation upon a single stimulus with a rise of skin temperature after repeated stimulation not exceeding the thresholdof C mechano-heat fibres. Subjects reported a progressive increase of the intensity of heat and burning pain during repeated laser stimulation in spite of only mild (4.8 degrees C) increase of skin temperature from the first stimulus to t
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0517" target="_blank" >1M0517: Center of Neuropsychiatric Studies 2005-2009 (Neurobiology in Clinical Application)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS One
ISSN
1932-6203
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
"e19744", 1-10
UT code for WoS article
000290440200023
EID of the result in the Scopus database
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