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Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003327" target="_blank" >RIV/00216208:11120/11:00003327 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.cellimm.2011.04.008" target="_blank" >http://dx.doi.org/10.1016/j.cellimm.2011.04.008</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.cellimm.2011.04.008" target="_blank" >10.1016/j.cellimm.2011.04.008</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection

  • Original language description

    Invariant natural killer T (iNKT) cells play an important role in the immune response against various infectious agents. In this study we investigated their role in human defense against the varicella zoster virus. We observed decreased numbers of iNKT cells in patients who failed to control latent varicella zoster virus infection, e.g. underwent several reactivations of the virus. The residual population of iNKT cells expressed significantly higher levels of inhibitory receptor CD158a that was furtherup-regulated in the course of acute viral infection. Both of these abnormalities might contribute to impaired control of varicella zoster virus in human

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cellular Immunology

  • ISSN

    0008-8749

  • e-ISSN

  • Volume of the periodical

    269

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    4

  • Pages from-to

    78-81

  • UT code for WoS article

    000291765300003

  • EID of the result in the Scopus database