Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003327" target="_blank" >RIV/00216208:11120/11:00003327 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.cellimm.2011.04.008" target="_blank" >http://dx.doi.org/10.1016/j.cellimm.2011.04.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cellimm.2011.04.008" target="_blank" >10.1016/j.cellimm.2011.04.008</a>
Alternative languages
Result language
angličtina
Original language name
Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection
Original language description
Invariant natural killer T (iNKT) cells play an important role in the immune response against various infectious agents. In this study we investigated their role in human defense against the varicella zoster virus. We observed decreased numbers of iNKT cells in patients who failed to control latent varicella zoster virus infection, e.g. underwent several reactivations of the virus. The residual population of iNKT cells expressed significantly higher levels of inhibitory receptor CD158a that was furtherup-regulated in the course of acute viral infection. Both of these abnormalities might contribute to impaired control of varicella zoster virus in human
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cellular Immunology
ISSN
0008-8749
e-ISSN
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Volume of the periodical
269
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
78-81
UT code for WoS article
000291765300003
EID of the result in the Scopus database
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