A comparison of collateral sprouting of sensory and motor axons after the end-to-side neurorrhaphy with and without the perineurial window

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43895873" target="_blank" >RIV/00216208:11120/12:43895873 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/12:43895873
Result on the web
<a href="http://dx.doi.org/10.1097/PRS.0b013e31825dc20a" target="_blank" >http://dx.doi.org/10.1097/PRS.0b013e31825dc20a</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/PRS.0b013e31825dc20a" target="_blank" >10.1097/PRS.0b013e31825dc20a</a>

Result language
angličtina
Original language name
A comparison of collateral sprouting of sensory and motor axons after the end-to-side neurorrhaphy with and without the perineurial window
Original language description
Many experimental studies confirmed collateral sprouting of axons after end-to-side neurorrhaphy and its possible clinical application. There is still controversy about how the surgical method should be carried out. The aim of present study was to make quantitative evaluation of collateral sprouting of motor and sensory axons after end-to-side neurorrhaphy with and without the perineurial window. Methods: End-to-side neurorrhaphy of the distal stump of transected musculocutaneous nerve with intact ulnarnerve with or without a perineurial window was performed in a rat model. Collateral sprouts were quantitatively evaluated by counting of motor and sensory neurons following their retrograde labeling by Fluoro-Ruby and Fluoro-Emerald applied to the ulnarand musculocutaneous nerve, respectively. Results: Our results show that significantly more motor and sensory axons sent their collateral branches into the recipient nerve in the group with a perineurial window. An amount of axons were i
Czech name
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Czech description
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Project
<a href="/en/project/NS10496" target="_blank" >NS10496: Assessment of the success rate of end-to-side anastomosis of peripheral nerves in relation to the other neurotization techniques used in clinical practice, and the application of neurotrophins incorporated by plasmids in an experimental model</a>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ) S - Specificky vyzkum na vysokych skolach I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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