Quantitative assessment of the ability of collateral sprouting of the motor and primary sensory neurons after the end-to-side neurorrhaphy of the musculocutaneous with ulnar nerve

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00017065" target="_blank" >RIV/00216224:14110/06:00017065 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Quantitative assessment of the ability of collateral sprouting of the motor and primary sensory neurons after the end-to-side neurorrhaphy of the musculocutaneous with ulnar nerve

Original language description

In view of the lack of theoretical information, end-to-side neurorrhaphy is a frequent object of experimental interest. End-to-side neurorrhaphy is based on collateral sprouting of an intact axon. The quantitative assessment of collateral sprouts sent byon intact motor and sensory axons was the goal of the present study. End-to-side neurorrhaphy of the distal stump of transected musculocutaneous nerve (MCN) with intact ulnar nerve (UN) was performed in a rat model. Collateral sprouts were quantitatively evaluated by counting of motoneurons and DRG neurons following their retrograde labeling by Fluoro-Ruby and Fluoro-Emerald applied to the UN and MCN, respectively. The results suggest a comparable capacity of both intact sensory and motor axons to sendcollateral sprouts into a denervated nerve stump. The ratio of sensory/motor neurons, the axons of which reinnervated distal MCN stumps, was very similar to that of intact UN (6.500 and 6.747, respectively), but different from intact MCN

Czech name

Kvantitativní analýza schopnosti tvorby kolaterál motorických a sensorických neuronů po end-to-side anastomóze n. musculocutaneous a n. ulnaris

Czech description

Retrográdním značením motorických a senzorických neuronů byla kvantitativně analyzována schopnost těchto neuronů vytvářet kolaterály po aplikaci end-to-side anastomózy mezi n. musculocutaneus a ulnaris. Bylo zjištěno, že poměr senzorických/motorických kolaterál odpovídá poměru mateřských axonů v donorovém nervu a není patrně ovlivněn počtem Bungnerových sloupců pro motorické a senzorické axony v recipientním nervu.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/1A8252" target="_blank" >1A8252: End-to-side anastomosis of peripheral nerve and evaluation of neurotrophic factors influence on efficacy of functional reinnervation</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Anatomy

ISSN

0940-9602

e-ISSN

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Volume of the periodical

188

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

337-344

UT code for WoS article

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EID of the result in the Scopus database

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