Impact of psychotropic drugs on adult hippocampal neurogenesis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43905989" target="_blank" >RIV/00216208:11120/12:43905989 - isvavai.cz</a>

Alternative codes found

RIV/00023752:_____/12:43913772

Result on the web

<a href="http://dx.doi.org/10.1016/j.neures.2012.02.014" target="_blank" >http://dx.doi.org/10.1016/j.neures.2012.02.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.neures.2012.02.014" target="_blank" >10.1016/j.neures.2012.02.014</a>

Result language

angličtina

Original language name

Impact of psychotropic drugs on adult hippocampal neurogenesis

Original language description

This review focuses on the relationship between psychotropic drugs and adult hippocampal neurogenesis. Adult neurogenesis is important for learning and memory, as well as for depression and anxiety. There is some evidence that chronic treatment with opiates, stimulants and entactogens decreases neurogenesis and consequently impairs cognitive function, as well as inducing depressive-like behaviour in animals during drug withdrawal. On the other hand, NMDA receptor antagonists increase neurogenesis, but negatively affect cognitive function and have an antidepressant-like profile. We suggest that drug-induced changes in neurogenesis have a greater and more concise effect on emotive state reflecting the direction of influencing new cells proliferation thanthe performance of cognitive tasks. In this review we provide some evidence for this assumption

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FL - Psychiatry, sexology

OECD FORD branch

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Project

<a href="/en/project/NS10378" target="_blank" >NS10378: Sex differences in the effect of 3,4-methylendioxametemphetamine (MDMA) on cognitive function, neurogenesis and farmacokinetics parameters</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroscience Research

ISSN

0168-0102

e-ISSN

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Volume of the periodical

73

Issue of the periodical within the volume

2

Country of publishing house

IE - IRELAND

Number of pages

6

Pages from-to

93-98

UT code for WoS article

000304520200001

EID of the result in the Scopus database

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