The relationship between S100B protein serum levels, injury severity and Glasgow Outcome Scale values in children with CNS injuries
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906497" target="_blank" >RIV/00216208:11120/12:43906497 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/12:#0000414
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The relationship between S100B protein serum levels, injury severity and Glasgow Outcome Scale values in children with CNS injuries
Original language description
The S100B protein subgroup is a thermolabile acidic calcium-binding protein, which was first described in association with the central nervous system. Destruction of nerve tissue results in S100B protein release from astrocytes and elevation of its levels in cerebrospinal fluid. If the blood-brain barrier is also damaged, S100B can pass into the systemic circulation and elevated blood levels of S100B can be detected. High S100B serum levels in patients with head injuries are predictive of possible development of secondary brain injury and may be related to the extent of permanent injury to the CNS. The authors present results obtained from a group of 39 children aged 0 (newborns) to 17 years with an isolated craniocerebral injury. RESULTS: In our groupof 39 children (aged 0-17 years) we observed excellent GOS group (GOS - Glasgow Outcome Scale 4 or 5) in 33 patients at the time of transfer from our intensive care unit to the neurological department. There were no deaths and only 6 chi
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroendocrinology Letters
ISSN
0172-780X
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
2
Country of publishing house
SE - SWEDEN
Number of pages
5
Pages from-to
207-211
UT code for WoS article
000305037700016
EID of the result in the Scopus database
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