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2. Monitoring of Arrays of Amino Acids in Clinical Samples Using Capillary Electrophoresis with Contactless Conductivity Detection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906525" target="_blank" >RIV/00216208:11120/12:43906525 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/978-1-62703-029-8_2" target="_blank" >http://dx.doi.org/10.1007/978-1-62703-029-8_2</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-1-62703-029-8_2" target="_blank" >10.1007/978-1-62703-029-8_2</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    2. Monitoring of Arrays of Amino Acids in Clinical Samples Using Capillary Electrophoresis with Contactless Conductivity Detection

  • Original language description

    Capillary electrophoresis (CE) with contactless conductivity detection (C4D) is readily applicable to determinations of amino acids in clinical samples. Most of these analyses employ long separation pathways. This chapter describes CE/C4D determinationsof 28 biogenic amino acids in a short capillary with an effective length of 18 cm. All the test amino acids can be mutually separated in electrolytes of 0.5 to 10 mol/L acetic acid. The time of analysis does not exceed 6 min., the limits of detection vary from 0.1 to 1.7 ?mol/L for all the analytes. The pretreatment of the biological material is very simple, consisting of removal of proteins by an addition of acetonitrile and subsequent filtration. The procedure has been successfully applied to determinations of the whole amino acid spectra in blood plasma, urine, saliva, cerebrospinal and amniotic fluid samples

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP206%2F10%2F1231" target="_blank" >GAP206/10/1231: New Electrophoretic Approaches to the Monitoring of Pain Neurotransmitters in the Brain Tissue of Higher Organisms</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Clinical Applications of Capillary Electrophoresis: Methods and Protocols

  • ISBN

    978-1-62703-028-1

  • Number of pages of the result

    11

  • Pages from-to

    13-23

  • Number of pages of the book

    311

  • Publisher name

    Humana Press

  • Place of publication

    New York

  • UT code for WoS chapter