Regional cerebellar metabolism ((18)FDG PET) predicts the clinical outcome of the short-term inpatient treatment of alcohol addiction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906587" target="_blank" >RIV/00216208:11120/12:43906587 - isvavai.cz</a>

Alternative codes found

RIV/00023752:_____/12:43913795

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Regional cerebellar metabolism ((18)FDG PET) predicts the clinical outcome of the short-term inpatient treatment of alcohol addiction

Original language description

OBJECTIVES: The acute and maintenance treatment of alcohol addiction represents the clinical challenge. The aims of our study were to evaluate the influence of alcohol consumption on regional brain metabolism and the predictive value of PET by means of the duration and quality of remission which followed the sub-acute treatment. METHODS: PET investigation with (18)fluoro-deoxyglucose ((18)FDG) were performed in detoxified patients with alcohol dependence at the end of short-term treatment. Abstinence was evaluated in patients during the one year follow-up period. RESULTS: We detected the positive correlation between (18)FDG uptake in the cerebellar vermis (FWE, p<0.05) and duration of abstinence within one year. DISCUSSION: Our findings support the assumption that the cerebellum would be involved in the maintenance of abstinence in alcohol dependent subjects. Cerebellar connections with cortical areas critical for addiction such as frontal, parietal, temporal regions would mediate the

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NS10253" target="_blank" >NS10253: Persistent prefrontal activation as an marker of craving and predictor of loss of persistence during the treatment of addiction</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

4

Country of publishing house

SE - SWEDEN

Number of pages

6

Pages from-to

419-424

UT code for WoS article

000310259500011

EID of the result in the Scopus database

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